Regret
Regret can have damaging effects on mind and body when it turns into fruitless rumination and self-blame that keeps people from re-engaging with life. This pattern of repetitive, negative, self-focused ruminative thinking is characteristic of depression—and may be a cause of this mental health problem as well. Other research shows that regret can result in chronic stress, negatively affecting hormonal and immune system functioning. Regret impedes the ability to recover from stressful life events by extending their emotional reach for months, years, or lifetimes.
The best way to limit these regrets is first by understanding what the biggest ones are and second, by taking action before its too late.